Angela Merkel, Chancellor of Germany tells in connection with the referendum in UK.
"We take note of the British people's decision with regret. There is no doubt that this is a blow to Europe and to the European unification process."
Ms Merkel said that because of its history, Germany has "a particular interest and a particular responsibility" to make European unity a success. But in her first public address since the nation backed a Leave vote, the German chancellor called for Brussels to maintain "close future relations" with Britain.
Mrs Merkel said we are "living in a world of turmoil" as she urged Europe to remain "calm and composed" in the wake of the historic Brexit result. She said: "We have to remain calm and composed. We need to make composed analysis and decisions.
"The EU is one of the world's largest economic areas, a guarantor of peace and stability. We must engage with the world. I believe the world will stand united." She added: "We need to make sure that Europe is varied, and as varied as the people of the EU are. "Time and time again we are confronted with people that have doubts over the direction that the EU has taken. "We have to make sure that people feel that the EU can make a contribution to people's lives." Mrs Merkel described the EU as a "unique community of solidarity and values".
The German leader confirmed she will meet with the European Council president Donald Tusk, French president Francois Hollande and Italy's Prime Minister Matteo Renzi in Berlin on Monday.